Food and Medication Administration to take care of two different tumor types. In 2012 September, Stivarga was initially approved for the treating individuals with metastatic colorectal tumor who’ve been previously treated with fluoropyrimidine-, oxaliplatin – and irinotecan-centered chemotherapy, an anti-VEGF therapy, and, if KRAS crazy type, an anti-EGFR therapy. In 2013 February, the FDA also accepted Stivarga to treat individuals with locally advanced, unresectable or metastatic gastrointestinal stromal tumor who’ve been previously treated with imatinib mesylate and sunitinib malate.2..This will help prevent blood from pooling in the region because even more of the blood will flow back toward your heart. If you keep standing, more bloodstream shall flow to your bruised shin and the bruise will be larger. Take acetaminophen for pain, if needed.To See a Doctor BackContinueWhen Minor bruises are treated easily, but it’s probably better to talk to a doctor if: A bruise isn’t improving after 14 days. You bruise and bruises appear to develop for no known factors often. Your bruise is swelling and very painful. You can’t move a joint or you imagine you may have a broken bone. The bruise is close to your eye and you have a problem moving your eyes or seeing. Can Bruises Be Prevented? Bruises are sort of hard to totally avoid, but if you are playing sports activities, riding your bike, inline skating, or doing anything where you might bump, bang, crash, or smash into something — or something might bump, bang, crash, or smash into you — it’s best if you wear protective equipment like pads, shin guards, and helmets.