These data are believed by The authors demonstrate that BRAF L597 mutations have scientific significance in melanoma. Further study is required to confirm these findings.. BRAF L597 mutation in melanoma sufferers responds to MEK inhibitor drugs An uncommon mutation of the BRAF gene in melanoma individuals has been found to react to MEK inhibitor medications, providing a rationale for program screening and therapy in melanoma sufferers who harbor the BRAF L597 mutation. The new research by co-first-authors Kimberly Dark brown Dahlman, Ph.D., Junfeng Xia, Ph.D., and Katherine Hutchinson, B.S., Vanderbilt-Ingram Cancer Middle , Nashville, Tenn., july 14 in Tumor Discovery was published online. The extensive study was led by co-senior authors William Pao, M.D., Ph.D., Jeffrey Sosman, M.D., and Zhongming Zhao, Ph.D., VICC, and Antoni Ribas, M.D., Jonsson Comprehensive Cancer Middle, UCLA, LA, Calif.‘It is broadly accepted that a amount of interacting factors will tend to be involved in the decline of bees and other pollinators – lack of flowers, episodes by parasites, and exposure to pesticide cocktails, for instance,’ Exley said. Much attention has focused on the grouped family of pesticides known as neonicotinoids – systemic pesticides that infiltrate every portion of a plant, including the pollen and nectar. Three neonicotinoids have already been banned in European countries due to evidence of harm to pollinators. Alarmingly, two recent studies published in the journal Character suggest that bees could possibly be particularly attracted to vegetation treated with neonicotinoids, preferentially going to them over untreated plants.