At a information conference at a community clinic here, state Sen. Ed Hernandez announced plans Wednesday to present a series of bills that would redefine professional boundaries for several mid-level health workers, permitting them to provide even more services than presently allowed under state regulation . Sacramento Bee: CA Lawmakers Look To Expand Scope Of Some Medical Professionals Citing a need for more medical professionals able to treat patients who’ll soon have medical health insurance under the federal Affordable Treatment Act, state Sen. On Wednesday introduced a package of bills to expand the services that optometrists Ed Hernandez, pharmacists and nurse practitioners can provide patients. The so-called ‘scope of practice’ bills set the stage for an enormous fight with the state's physicians, who’ll look to protect their role as gatekeepers to health care.Bosutinib resistance associated with ABCB1 transporter By Lynda Williams, Senior medwireNews Reporter Level of resistance to the tyrosine kinase inhibitor bosutinib could be mediated by overexpression of the efflux transporter ABCB1, scientists suggest. Cells overexpressing ABCG2 or SLC22A1 didn’t display any difference in the uptake of radiolabelled bosutinib, state Sara Radaelli, from University of Milano-Bicocca in Monza, Italy, and co-workers. In comparison, cells overexpressing ABCB1 experienced a significant reduction in bosutinib incorporation, indicating that transporter regulates intracellular bosutinib amounts.